With the help of antiretroviral therapy treatments, an HIV diagnosis is no longer a death sentence. In fact, patients who are tested for the disease and begin treatment at an early stage now have a similar life expectancy to those without the infection. However, while HIV is now referred to as a chronic, manageable illness, it still has no cure. Researchers are working hard to change this and a safety study published today in Molecular Therapy represents an important step forward in the hunt for an effective treatment. Scientists from the University of North Carolina successfully demonstrated the safety of a cell therapy involving the ex vivo expansion of T cells and their infusion in HIV positive patients in combination with antiretroviral (ART) drugs. We talked to co-senior study author David Margolis to find out more.